Vinorelbine (Navelbine®) is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer.

Product Name: Vinorelbine;5'-Noranhydrovinblastine;Navelbine;NVB;KW-2307

Chemical Name: 3',4'- Didehydro-4'-deoxy-C'-norvincaleukob-lastine

Molecular Formula:C₄₅H₅₄N₄O₈

Molecular Weight: 778.94

CAS No. : 71486-22-1

Properties: Yellow white formless crystalline powder, soluble in water, alcohol, methanol, methylene chloride

Structural Formula:


Use: Antineoplastic medicine. Used in treating non mini cell stomach cancer. Low toxicity.

Side Effects:
1) Vinorelbine has a number of side-effects that can limit its use:
2) Lowered resistance to infection, bruising or bleeding, anaemia, constipation, diarrhoea, nausea, numbness or tingling in hands or feet (peripheral neuropathy), tiredness and a general feeling of weakness (asthenia), inflammation of the vein into which it was injected (phlebitis).
3) Less common effects are hair loss and allergic reaction.



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