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Name: | PEMETREXED DISODIUM |
| Synonyms: | N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt | |
| CAS: | 150399-23-8 | |
| Molecular Formula: | C20H19N5Na2O6 | |
| Molecular Weight: | 471.37[g/mol] | |
| Specifications: | BP, USP, enterprise stardard | |
| MSDS: | Pemetrexed disodium.PDF | |
| Capacity: | In custom-tailor, stock, | |
| Period of validity: | 2 years-- (Kept airtightly in a light-proof, dry and cool place) | |
| Package: | custom-tailor, 25kg/drum | |
| Free encyclopedia | Pemetrexed is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis—thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase(GARFT). By inhibiting the formation of precursor purine and pyrimidine nucleotides, pemetrexed prevents the formation of DNA and RNA, which are required for the growth and survival of both normal cells and cancer cells. | |
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